I have been using Retina w/o Rem for quite some time and have a method for doing delta's. The most difficult part is ensuring you have a solid process in place and the ability to write your own SQL.
Retina results are stored in .rtd files which for all intents and purposes is an access db readable format. You can a) Merge the access db's, b) import them into SQL 2008 server, or c) link them in as linked DBs to SQL 2008 or Access. (of course I am sure you can find a hundred different ways to skin this cat).
Once you have the data all in one place, it is a matter of just building queries that represent the reporting you would like to see on the data. I have some basic ones like Count descending, top 10 offenders, bottom 10 offenders, top ten improvements, bottom ten improvements, and various dashboards and charts for management all from the data collected across any number of periodic scans. I use these to create the reports for all levels as well as to support the kill cycle used during the remediation process.
If you have the cability to deply REM, especially in a distributed environment, that is your best bet as Blue1978 and bpatten have mentioned because the work I described above for the most part is being done for you.
In my situation, I needed a lot more flexibility and also integration with sharepoint and other automation tools so the raw data works best for me.
LD